Ampicillin (Principen)

Description Ampicillin is in the family of antibiotics known as penicillins. The drug blocks the formation of the bacterial cell wall and is approved in a number of bacterial infections, other than food poisoning, caused by streptococci, pneumococci, Listeria, Salmonella, Shigella, and E. coli, among others.

Original uses (on-label) Infections of the respiratory tract and soft tissues caused by susceptible organisms; bacterial meningitis caused by susceptible organisms; septicemia; gonococcal infections; prevention of bacterial endocarditis.

Newly discovered uses (off-label) Also, you can buy principen to treat cholera, food poisoning.

Drug interactions

• Methotrexate: concentrations of methotrexate in the blood are increased, which may cause toxic effects.
• Oral contraceptives: their contraceptive effect may be reduced.
• Additional contraceptive precautions should therefore be taken with short courses of ampicillin and for seven days after stopping; if these days run beyond the end of a packet of oral contraceptives, the next packet should be started immediately without a break.

Food interactions Food decreases ampicillin absorption rate and may decrease ampicillin serum concentration.

Herbal interactions Khat

Pregnancy and breast-feeding cautions FDA Pregnancy Risk Category B. Amoxicillin is excreted in breast milk. The American Academy of Pediatrics considers this drug compatible with breast-feeding.

Buy Ampicillin online

Ampicillin is a prescription drug that comes in 250 mg, 500 mg capsules. It is available on prescription only as capsules for oral use, but the online pharmacy, will sell Principen without prescription. You may be able to order Ampicillin from them online and save the local pharmacy markup.

Treatment of cholera Principen can reduce the volume of diarrhea in patients with severe cholera. This drugs can also shorten the excretion time of the microorganism involved with cholera known as Vibrio cholerae.

In general, antibiotic therapy for cholera is considered in addition to fluid therapy. Antibiotics such as Principen reduce diarrhea volume and duration by about 50%, they can shorten hospitalization time.

In a review article published by a researcher in The Netherlands, Principen, among other traditional antibiotics, was mentioned as the mainstay therapy for the management of bacterial Salmonella infections from food. Also mentioned was that the increasing resistance to these traditional antibiotic drugs necessitates the use of different types of antibiotics for this type of bacterial disease.

Food Poisoning Treatment Case reports also document the use of ampicillin for Salmonella infections. In one instance, a pregnant woman came down with gastroenteritis one week before delivery. The newborn infant was subsequently treated with Principen, gentamicin (an antibiotic), and amoxicillin (an antibiotic); however, five months later, Salmonella was still present. In this case, researchers discussed the potential route of infection and the guidelines for treatment and management of this type of bacterial infection in pregnancy and post-partum.