Description
Dostinex may be prescribed by your doctor to reduce your body's level of a hormone known as prolactin. Dostinex may be needed if your levels of prolactin are abnormally high (hyperprolactinaemia).
Abnormally high prolactin may cause menstrual changes in women, impotence in men and breast changes in both sexes.
Dostinex can also be prescribed to prevent the production of milk in women after birth, if breast-feeding is to be prevented for medical reasons.
Original uses (on-label)
Treating disorders associated with high levels of the hormone prolactin, either due to tumors in the pituitary gland or to unknown causes. It may also be used for other conditions as determined by your doctor. Dostinex is a dopamine receptor agonist. It works by blocking prolactin secretion from the pituitary gland.
Potential side effects
Some of the side effects that can occur with cabergoline may not need medical attention. All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most common side effects persist or become bothersome: Constipation; dizziness; headache; indigestion; mild stomach pain; nausea; tiredness or weakness; vomiting.
Cautions
Do NOT use Dostinex if:
- you are allergic to any ingredient in Dostinex or to ergot derivatives (eg, ergotamine)
- you have uncontrolled high blood pressure
- you have a history of heart valve problems or certain fibrotic (scarring) disorders (eg, of the lung, heart, kidneys)
- you are taking a butyrophenone (eg, haloperidol), metoclopramide, a phenothiazine (eg, chlorpromazine), or a thioxanthene (eg, thiothixene)
- you have taken or will be taking a "triptan" (eg, sumatriptan) within 24 hours before or after taking Dostinex
Contact your doctor or health care provider right away if any of these apply to you.
Drug interactions
Using cabergoline together with clarithromycin is not recommended. Combining these medications may significantly increase the blood levels and effects of cabergoline, which in some cases can lead to excessive narrowing of blood vessels in the body. This can reduce blood flow to vital organs and increase the risk of rare but serious side effects such as high blood pressure, heart attack, stroke, and gangrene.
Food interactions
Alcohol can increase the nervous system side effects of Dostinex such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with cabergoline. Do not use more than the recommended dose of cabergoline, and avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you. Talk to your doctor or pharmacist if you have any questions or concerns.
Buy Dostinex online
Where can I buy Cabergoline without prescription?
Dostinex is a prescription drug that comes in 0.5 mg, 0.25 mg, 1 mg pills.
It is available on prescription only as tablets for oral use, but the online pharmacy, will sell Cabergoline without prescription.
You may be able to order Dostinex from them online and save the local pharmacy markup.
Most online pharmacies offer discounted prices when you buy Dostinex in large quantities.
Usage Instructions
Some medical conditions may interact with Dostinex. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have liver problems or high blood pressure
- if you have developed high blood pressure caused by pregnancy
- if you take any medicine that may lower blood pressure or cause heart valve problems. Check with your doctor or pharmacist if you are unsure if any of your medicines may lower blood pressure or cause heart valve problems
Use Dostinex as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Take Dostinex by mouth with or without food.
- It may be helpful to mark on a calendar which days you are supposed to take Dostinex.
- If you miss a dose of Dostinex, contact your doctor right away.
Ask your health care provider any questions you may have about how to use Dostinex.
Special information
Dostinex in Bodybuilding. A common goal for bodybuilders is to increase testosterone levels that ultimately lead to an increase in muscle growth and size. By reducing the total amount of prolactin, the body is able to increase testosterone levels. Dostinex / Cabergoline can also be used in combination with anabolic steroids and nutritional supplements without affecting their benefits.
Dostinex is usually employed by bodybuilders to combat prolactin and effects related to prolactin. Prolactin is a single-chain protein, very closely related to growth hormone. It is secreted by what's known as lactotrophs in the anterior part of your pituitary gland. In addition, Prolactin is also synthesized and secreted by many other cells in the body, like immune cells, in the brain, and in women is even secreted by the decidua, in the uterus of pregnant women.
Dostinex Review
What is Dostinex?
Dostinex belongs to a class of medications known as prolactin inhibitors. Prolactin inhibitors such as cabergoline are used to treat different types of medical problems that occur when too much prolactin, a hormone, is produced by the pituitary gland in the brain. An excess production of prolactin can result in menstrual problems in women and fertility problems in men and women.
Brands & Classes
Brand name
Dostinex
Generic name
Cabergoline
Avail forms
Tablets - Oral 0.5 mg, 0.25 mg, 1 mg.
Dosage
ADULT
The recommended dosage of Dostinex Tablets for initiation of therapy is 0.25 mg twice a week. Dosage may be increased by 0.25 mg twice weekly up to a dosage of 1 mg twice a week according to the patient's serum prolactin level. Before initiating treatment, cardiovascular evaluation should be performed and echocardiography should be considered to assess for valvular disease.
Dosage increases should not occur more rapidly than every 4 weeks, so that the physician can assess the patient's response to each dosage level. If the patient does not respond adequately, and no additional benefit is observed with higher doses, the lowest dose that achieved maximal response should be used and other therapeutic approaches considered. Patients receiving long term treatment with Dostinex should undergo periodic assessment of their cardiac status and echocardiography should be considered.
After a normal serum prolactin level has been maintained for 6 months, Dostinex may be discontinued, with periodic monitoring of the serum prolactin level to determine whether or when treatment with Dostinex should be reinstituted. The durability of efficacy beyond 24 months of therapy with Dostinex has not been established.